The action mechanism of antimicrobial peptides results in the destabilization of the biofilm structure. Biofilm sections are affected in different ways by the action of antimicrobial peptides, depending on the exposure of cells to the peptide. Usingconfocal microscopy, we want to determine the biofilm section that presents the greatest damage due to peptide activity, as well as defining sub-populations within the biofilm that show the greatest susceptibility to the antimicrobial peptide.

María Isabel Perez, Steve Trier