Molecular dynamics of membranes to study their mechanical properties
We have developed a molecular dynamics technique to determine the elastic properties of different lipid systems. We use umbrella sampling to determine the Potential Mid Force (PMF) and to study deformation profiles in order to understand how the presence of different membrane modifiers (lisolipids, detergents, peptides) affect these mechanical properties.
Rafael Clavijo, Juan David Orjuela, Colaboradores: Gilles Pieffet, Günther Peters, Roland Faller
